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2021, Vol: 8, Issue: 2
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Research Article 


REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza.

Abstract
Type 1 diabetes (T1D) with a solid genomic factor, is a multifactorial disease. which arise through autoimmune
annihilation of pancreatic β cells. Epidemiologic forms of T1D type 1 diabetes by cultural, demographic,
geographic, biological and some additional aspects in population are offered to increase awareness with regard to
risks, past linkages, etiologic and impediment of DM1. Information after huge epidemiological trainings indicate
internationally that the occurrence of type 1 diabetes T1D increased globally by 2-5% and the occurrence of T1D is
around 1 in 300, by 18 years of phase in the US. Study on hazard aspects for type 1 diabetes T1D is a dynamic part
of study to classify inherited and conservational reasons that might be theoretically targeted for interference. Though
important developments been completed in the experimental maintenance of type 1 diabetes T1D with experimental
consequences and resulting developments in class of natural life, significant extra requirements to improve care of
and eventually discover a medication for type 1 diabetes T1D. Epidemiological trainings take a significant on -going
part to examine the clinical care, prevention, complex causes and therapy of type 1 diabetes T1D. INS, HLA CTLA4
and PTPN22 are measured to be established by type 1 diabetes (T1D) vulnerability genetic factor. CTLA4, PTPN22
and HLA are identified to be complicated in protected inst ruction. Hypothesis mostly recognized vulnerability
genetic factor appear to almost increase with other loci on the risk of disease including the joint effect of PTPN22
and HLA. The combined outcome of many vulnerability loci discussed the actual risk of t ype 1 diabetes but also
applies to the same unimportant part of the overall population. By means of numerous vulnerability genotypes
associated with HLA genotypic factor appeared to slightly effect the prediction of disease.

Key words: T1D. INS, HLA CTLA4 and PTPN22 are measured to be established by type 1 diabetes (T1D) vulnerability genetic factor.


 
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How to Cite this Article
Pubmed Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. JCR. 2021; 8(2): 49-64. doi:10.31838/jcr.08.02.07

Web Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. http://www.jcreview.com/?mno=66689 [Access: April 16, 2021]. doi:10.31838/jcr.08.02.07

AMA (American Medical Association) Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. JCR. 2021; 8(2): 49-64. doi:10.31838/jcr.08.02.07


Vancouver/ICMJE Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. JCR. (2021), [cited April 16, 2021]; 8(2): 49-64. doi:10.31838/jcr.08.02.07


Harvard Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza (2021) REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. JCR, 8 (2), 49-64. doi:10.31838/jcr.08.02.07


Turabian Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. 2021. REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. Journal of Critical Reviews, 8 (2), 49-64. doi:10.31838/jcr.08.02.07


Chicago Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. "REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1." Journal of Critical Reviews 8 (2021), 49-64. doi:10.31838/jcr.08.02.07


MLA (The Modern Language Association) Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza. "REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1." Journal of Critical Reviews 8.2 (2021), 49-64. Print. doi:10.31838/jcr.08.02.07


APA (American Psychological Association) Style

Ayesha Nawaz,BushraGul,Tayyaba Shan,Dr. AsmaNoureen,Dr.KhalidHussain Rind,Muhammad WaseemShoaib, Muhammad Tahir,Mehnaz Jamil,RamshaFayyaz,HiraMubeen,ShahidRaza (2021) REVIEW ON EFFECT OF GENETIC AND NONGENETIC FACTORS ON THE RISK OF DIABETES TYPE 1. Journal of Critical Reviews, 8 (2), 49-64. doi:10.31838/jcr.08.02.07


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