Abstract

Cretinism is a rare and severe form of hypothyroidism that primarily influences infants and children. Types of cretinism are congenital cretinism and acquired cretinism. Symptoms of cretinism include developmental delays, intellectual disabilities, growth retardation, coarse facial features, hearing as well as speech impairements and constipation. Diagnosis is based on blood tests, imaging studies and genetic testing. Treatment is dependent on hormone replacement therapy, regular monitoring, supportive care and nutritional suppport. It is finally concluded th at cretinism is a rare but serious condition that impacts thyroid hormone production resulting in the developmental intellectual disabilities due to the absence of treatment. Either early diagnosis or proper treatment particul arly with hormone replacement therapy can enhance the quality of life for individuals in a significant manner.

Description