Abstract

2-nitro-4-methoxy aniline 1 on treatment with sodium thiocyanate in acetic acid afforded 2-amino-4-nitro-6-methoxy benzothiazole 2. Compound 2 in ethylene glycol was heated at 150 0C with 80% hydrazine hydrate to get 4-nitro-6-methoxy-2-hydrazino benzothiazole 3. This hydrazino compound 3 on heating with 2-hydroxy-3-methoxy benzaldehyde/4-hydroxy-3-methoxy benzaldehyde/2-hydroxy benzaldehyde/ napthaldehyde/ cinnamladehyde /4-dimethylamino benzaldehyde to obtain corresponding hydrazones (4a-4f). These hydrazones (4a- 4f) in benzene independently were refluxed on water bath for three hours with Attenburrow’s MnO2 to obtain 3-(2'-hydroxy-3'-methoxy phenyl (5a)/4'-hydroxy-3'-methoxy phenyl (5b)/2'-hydroxy phenyl(6c)/1'-napthyl (5d) / cinnamyl (5e) / 4'-dimethyl amino phenyl(5f) )-5-nitro¬-7-methoxy-1,2,4-triazolo-[3,4-b]-benzothiazoles respectively. All these newly synthesized compounds were treated with seed and observe its effect on seed germination.

Description