ISSN 2394-5125
 

Research Article 


EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi.

Abstract
Introduction: Vitiligo is a common acquired depigmentary disorder of the skin and mucosa, which is caused by loss of
functioning melanocytes.Recently there has been growing interest in the role of vitamin D3 in the pathomechanism of
vitiligo and its relevance in the treatment of vitiligo.
Aim of the work: to evaluate the serum level of 25-hydroxy vitamin D in patients with vitiligo before and after NB-UVB
therapy and correlation of this with re-pigmentation in vitiligo patients.
Patients and Methods: 40 patients with vitiligo treated with NB-UVB for 12 weeks, vitiligo area severity index was be
measured at 0 week and 12 weeks, and serum level of 25 (OH) D was measured at same intervals.
Results: The mean vitamin D level improved from a mean of 14.2 mg/dL to 16.2 mg/dL. VASI score improved from a
mean of around 9 before treatment to as less as 7.125 after treatment. We found a positive and significant correlations
between VASI scores and vitamin D levels both before (correlation coefficient: 0.395; P value = <0.001) and after
treatment (correlation coefficient: 0.412; P value = <0.001). We found a negative correlation between disease duration and
the change of VASI.
Conclusion: Cumulative doses of NB-UVB therapy improve low vitamin D levels in patients with vitiligo, which might
have a role in NB-UVB-induced repigmentation.

Key words: to evaluate the serum level of 25-hydroxy vitamin D in patients with vitiligo before and after NB-UVB


 
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Pubmed Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. JCR. 2021; 8(1): 589-594. doi:10.31838/jcr.08.01.65


Web Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. http://www.jcreview.com/?mno=54100 [Access: May 30, 2021]. doi:10.31838/jcr.08.01.65


AMA (American Medical Association) Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. JCR. 2021; 8(1): 589-594. doi:10.31838/jcr.08.01.65



Vancouver/ICMJE Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. JCR. (2021), [cited May 30, 2021]; 8(1): 589-594. doi:10.31838/jcr.08.01.65



Harvard Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi (2021) EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. JCR, 8 (1), 589-594. doi:10.31838/jcr.08.01.65



Turabian Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. 2021. EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. Journal of Critical Reviews, 8 (1), 589-594. doi:10.31838/jcr.08.01.65



Chicago Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. "EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS." Journal of Critical Reviews 8 (2021), 589-594. doi:10.31838/jcr.08.01.65



MLA (The Modern Language Association) Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi. "EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS." Journal of Critical Reviews 8.1 (2021), 589-594. Print. doi:10.31838/jcr.08.01.65



APA (American Psychological Association) Style

Sameh Mohamed Kamal Attia, Asmaa Ramadan Ali Morsi (2021) EFFECT OF NARROW BAND ULTRAVIOLET B ON THE SERUM LEVEL OF 25-HYDROXYVITAMIN D IN VITILIGO PATIENTS. Journal of Critical Reviews, 8 (1), 589-594. doi:10.31838/jcr.08.01.65