ISSN 2394-5125
 

Research Article 


COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA

Qandeel Abbas Soomro, Nabi Mirjut, 2Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain.

Abstract
Introduction: Pseudomonas aeruginosa is one of the most common hospital acquired infections in our setups.
Due to increasing resistance of the organism, the mortality and morbidity of the patient is also increasing.
Detection of the organism is very important to manage the diseases caused by organism.
Objective: To evaluate the in vitro efficacy of various anti-Pseudomonas antibiotics by paper disk diffusion
method against Pseudomonas aeruginosa isolated from various clinical specimens and to identify appropriate
antimicrobial in our setups.
Patients and Methods: It was a prospective study conducted at Department of Pathology, Indus Medical
College Tando Muhammad Khan for the period of 6 months. A total of 103 strains of Pseudomonas aeruginosa
were studied using various clinical specimens. Antimicrobial agents used were Carbenicillin (CAR), Piperacillin
(PIP), Imipenem (IMI), Aztreonam (AZT), Gentamicin (GEN), Tobramycin (TOB), Amikacin (AMI),
Ceftazidine (CAZ), Ofloxacin (OFL), Cipiprofloxacin (CIP) and Enoxacin (ENO).
Results: Amikacin, Ceftazidime, Imipenem, Pipercillin, Aztreonam, Ciprofloxacin, Enoxacin, Carbenicillin,
Ofloxacin, Tobramycin and Gentamicin were sensitive in percentages as92.23%, 87.3%), 83.5%, 80.6%, 73.7%,
64%, 60%, 53.3%, 47.5%, 40.7% and 39.8 % respectively.
Conclusion: This study shows that use of Carbenicillin, Ciprofloxacin, Enoxacin, Ofloxacin, Tobramycin and
Gentamicin against Pseudomonas aeruginosa on empirical basis will not be without the risk of treatment failure.

Key words: Pseudomonas aureginosa, antibiotics, hospital acquired infections


 
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How to Cite this Article
Pubmed Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. JCR. 2021; 8(2): 1740-1743. doi: 10.31838/jcr.08.02.176


Web Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. http://www.jcreview.com/?mno=98630 [Access: July 17, 2021]. doi: 10.31838/jcr.08.02.176


AMA (American Medical Association) Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. JCR. 2021; 8(2): 1740-1743. doi: 10.31838/jcr.08.02.176



Vancouver/ICMJE Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. JCR. (2021), [cited July 17, 2021]; 8(2): 1740-1743. doi: 10.31838/jcr.08.02.176



Harvard Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain (2021) COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. JCR, 8 (2), 1740-1743. doi: 10.31838/jcr.08.02.176



Turabian Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. 2021. COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. Journal of Critical Reviews, 8 (2), 1740-1743. doi: 10.31838/jcr.08.02.176



Chicago Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. "COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA." Journal of Critical Reviews 8 (2021), 1740-1743. doi: 10.31838/jcr.08.02.176



MLA (The Modern Language Association) Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain. "COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA." Journal of Critical Reviews 8.2 (2021), 1740-1743. Print. doi: 10.31838/jcr.08.02.176



APA (American Psychological Association) Style

Qandeel Abbas Soomro, Nabi Mirjut, Babar Aijaz Memon, Asim Patrick, Abdul Sami Dahri, Bushra Hussain (2021) COMPARISON OF IN VITRO EFFICACY OF ANTIBIOTICS AGAINST 103 CLINICAL ISOLATES OF PSEUDOMONAS AERUGINOSA. Journal of Critical Reviews, 8 (2), 1740-1743. doi: 10.31838/jcr.08.02.176