Clinical uses of Molecular Biology in the Treatment of Infectious Diseases (2023)
Dr J Nelson Samuel Jebastin,Dr Naladi Baratha Jyothi, Sunita Patnaik,Dr. Vamseedhar Annam JCR. 2023: 276-287
Molecular biological technologies for microbe identification and characterisation have revolutionized diagnostic microbiology and are now standard specimen processing. Polymerase chain reaction (PCR) procedures have ushered in this new age by rapidly detecting microbes that were previously impossible to identify. Molecular approaches can now discover infections of public health relevance faster than fastidious microbes. Molecular technologies now identify antimicrobial resistance genes and give public health information like strain genotyping. Viral resistance identification and viral load measurement for antiviral therapy monitoring have enhanced microorganism treatment. Multiplex PCR, real-time PCR, and automation are lowering molecular technique costs, increasing their use. This review will discuss the clinical efficacy of clinical microbiology laboratory molecular technologies and how they have transformed infectious illness diagnosis and therapy.
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