Demographic profile, outcome and mortality rate of mechanically ventilated children in pediatric intensive care unit (2023)
Dr. Nikitha V, Dr. Beere Gowda YC, Dr. Narendra RR JCR. 2023: 119-127
Mechanical ventilation helps in the decline of mortality rate in pediatric intensive care units (PICU) in many parts of the world but it has its associations with various complications and the outcome often unpredictable. Aim: The aim of the study is to assess the demographic profile, frequency, indications, and complications of mechanical ventilation and to assess the outcome of ventilated patients. Methods: This retrospective observational study was conducted in pediatric Intensive Care Unit (PICU), Department of Pediatrics, RL Jalappa Hospital and Research Center, Tamaka, Karnataka, during the period of 1 year from May 2021 to May 2022. Pediatric patients who were put on mechanical ventilation between the age of 1 month to 18 years were included in the study. Data of these children was collected including clinical biochemical parameters, indications of ventilation, complications, duration of ventilation and outcome. The patients were divided into two groups. Patients who remained successfully extubated and did not require re-intubation were grouped as survivors and who died during mechanical ventilation were grouped as non-survivors. Results: During the study period 133 patients were admitted to PICU, out of them 48 patients required mechanical ventilation. Out of these 48 patients 49% were females and 51% were males. Commonest condition for initiating mechanical ventilation was worsening respiratory distress and GCS less than 8. Mortality rate of these patients was 29%. Conclusion: Most common need for ventilated among the children was due to respiratory causes, and was also associated with higher mortality rate. Lesser duration of ventilation was associated with reduced mortality. Most common ventilator associated complication observed was ventilator associated pneumonia (VAP). Most common complications associated with mortality were DIC and pulmonary hemorrhage
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