ISSN 2394-5125
 
2021, Vol: 8, Issue: 8
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    DETERMINATION OF CURCUMIN BASED ON COUPLING WITH A CLASS OF SULFA DRUGS (2016)
    Syeda Ayesha
    JCR. 2016: 88 - 92

    Abstract

    Sulfanilamide (SAA), sulfadoxine (SDX) and sulfamethoxazole (SMX), the widely used sulfa drugs are proposed as new coupling agents for the spectrophotometric determination of curcumin. The methods are based on the interaction of diazotized sulfa drugs with curcumin to produce a yellow-coloured product with a maximum absorption at 425 nm. The colour developed was stable up to 24h. The methods obey Beer's law. The methods can be successfully employed for the determination of curcumin in presence of common excipients like glucose, lactose, dextrose, starch, sodium alginate and sodium lauryl sulphate, which do not interfere in the proposed methods

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    Volume & Issue

    Volume 3 Issue-2

    Keywords

    curcumin; diazotization; sulfanilamide; sulfadoxine; sulfamethoxazole; spectrophotometry
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