Function of Molecular Biology in Cancer Treatment (2023)
Dr Manisha,Dr J Nelson Samuel Jebastin,Dr.K.Kalaiarasi,Rajaram Das JCR. 2023: 217-228
RNAi, zinc finger nucleases, and CRISPR's ability to eliminate cancer is positive. These are promising research fields. However, cancer is a complicated and diverse illness, thus curing or eliminating it is difficult.RNA interference (RNAi) may selectively mute or downregulate gene expression. It targets oncogenes and inhibits cancer cell growth in lab tests. RNAi-based medicines must overcome delivery issues and off-target consequences before being extensively employed in clinical settings. ZFNs and CRISPR enable exact DNA sequence changes. They may disrupt oncogenes and target cancer-related genetic alterations. These methods worked in preclinical and early clinical trials, but further study is required to guarantee their safety, efficiency, and long-term effects. These molecular biology tools may improve cancer research and therapy, but a multifaceted approach to cancer control and management is needed. Early diagnosis, prevention, personalised treatment, targeted medicines, immunotherapies, and a better understanding of cancers complicated molecular underpinnings. In conclusion, RNAi, zinc finger nucleases, and CRISPR are potential cancer-fighting weapons, but further study and integration with other methods are needed to attain a cancer-free society. Molecular biology advances help us understand and cure cancer.
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