IONIC LIQUIDS (ILS) USED FOR ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUTION OF PHENOL DERIVATIVES: AN APPRISE (2020)
Santosh. R. Sonwane, Raviraj S. Kamble
JCR. 2020: 13245 - 13248
Abstract
The application of ionic liquids (ILs) in organic synthesis has garnered considerable attention due to their unique properties such as low volatility, high thermal stability, and tunable solubility. This review focuses on the halogenation, nitration, and nucleophilic substitution of phenol derivatives using ionic liquids. The advantages and mechanisms of these reactions in ILs are discussed, highlighting the role of ILs in enhancing reaction efficiency, selectivity, and environmental friendliness. By exploring recent advances and case studies, this review provides insights into the potential of ILs as green solvents and catalysts, promoting sustainable and efficient synthetic methodologies for phenol derivatives.
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Ionic Liquids (ILs), Phenol Derivatives, Halogenation, Nitration, Nucleophilic Substitution, Green Chemistry, Sustainable Synthesis