PHYTOCHEMICAL ANALYSIS AND ANTI-DIABETIC ACTIVITY OF Jasminum sambac (2020)
Basavaraj S. Hunasagi, Dr. Niraj Guptha JCR. 2020: 2253-2260
The present study describes the anti-diabetic potential of ethanoloic extract of Jasminum sambac Linn. Leaves on streptozocin induced diabetic rats and excision wound model to substantiate its folklore claim. The ethanolic extracts at two doses 100 and 200 mg/kg, p.o. prevented diabetes by Glucose oxidase method further studying its lipid profiles and anti-oxidant effects in rats. The wound healing potential of diabetic rats were conﬁrmed by the excision wound model studies with surface epithelization and wound contraction. Pretreatment with ethanolic extract of Jasminum grandiflorum Linn. leaves significantly (P < 0.05) increased the anti-oxidant enzymes and lipid peroxidation index. Further in wound healing activity the epithelialization period was significantly (p<0.01; P<0.001) lower in 10% and 5 % ointment of EEJG as that wound induced group. The results showed that ethanolic extract of Jasminum grandiflorum Linn. Leaves had significant anti-diabetic and wound healing effects.
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